Pharmacological Activities of Reishi (Ganoderma Lucidum): Potent Medicinal Mushroom

Abstract

Medicinal mushroom, Ganoderma lucidum is a white rot mushroom used in medicinal properties and economic importance. It contains a wide variety of bioactive molecules, which have been proved to have several therapeutically properties to control various diseases and it has toxic effects on humans. However, broad spectrum of its pharmacological actions have been established which include immunomodulation, anticancer, ant diabetic, antioxidant, anti-inflammatory, antimicrobial properties and estrogenic activity. Therefore, in this review particular focus on assess the components of biologically active compounds, pharmacological activity, economical importance, and toxicity of Ganoderma lucidum medicinal mushroom. G. lucidum biological active compounds might be a valuable constituent for the treatment of sex-hormone related aging ailments such as osteoporosis. Various animal studies have been carried out on G. lucidum water and ethanol extracts and protective effects toward acute hepatitis in rat and mice have been reported. Immunomodulatory and anti-inflammatory activities of G. lucidum recommend potential application in the treatment of autoimmune disorder like rheumatoid arthritis Ganoderma lucidum has a significant result on the cardiovascular system, such as reduce blood cholesterol, triglyceride level and blood pressure. Benign prostatic hyperplasia (BPH) is one of the common widespread disease, symptoms are seen usually in older men age group. Ganoderma lucidum has a significant result on the cardiovascular system, such as reduce blood cholesterol, triglyceride level and blood pressure.